Data Scientist H F

Description de la mission

A data scientist position is available within the laboratory of Dr Mickaël Ménager : Autoimmunity/inflammation Through RNAseq Analysis at the single Cell level for Therapeutic Innovation
Our lab is one of the main research team, involved in a big research hospital-university project (RHU), funded by the French national agency of research (ANR) and involving collaborations with national and international top-level scientists and clinicians from Imagine, Curie, Pasteur, CEA, INRA and industrial from Sanofi and Ariana Pharma. In this project, we are proposing to revisit rare monogenic disorders, characterized by autoimmunity and/or autoinflammation, at the single-cell level. By combining transcriptomic with proteomic, and epigenomic analyses performed on cells from the peripheral blood, in addition to lipidomic and metabolomic, we are aiming to identify so-called “pathological” cell clusters, mostly enriched of cells from patients as compared to controls. From such “pathological” cluster of cells, we intend to extract new molecular signatures, biomarkers that will help to redefine patients ‘stratification at the molecular level. We are now looking for a very talented and ambitious data scientist with biological knowledge/experience, who will embark with us, on this journey to redefine autoimmunity and autoinflammation at the molecular level, in collaboration with the Imagine data scientist platform and the Imagine bioinformatic hubs.